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KMID : 0870420100140040262
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Korean Journal of Hepato-Biliary-Pancreatic Surgery
2010 Volume.14 No. 4 p.262 ~ p.266
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A Case of Liver Metastasis of Gastrointestinal Stromal Tumor That Was Resected after Treatment with Imatinib Mesylate and Sunitinib
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Jung Gum-O
Chae Kwon-Mook
Park Dong-Eun
Shim Hyeok
Park Sang-Hyun
Yun Ki-Jung
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Abstract
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A 65-year old man underwent wedge resection for a gastrointestinal stromal tumor (GIST) of the gastric fundus in 1997. In 2003, the abdominal CT and sono-guided biopsy revealed he had a large GIST liver metastasis. He underwent treatment with 400 mg/day of imatinib mesylate. As a result, the liver metastasis markedly decreased in size. However, focal progression of the liver metastasis was observed on the follow up CT, so we increased the imatinib from 400 mg/day to 800 mg/day. We then performed extended left hepatectomy. We report here on a patient who presented with an isolated metastatic GIST to the liver, and the patient was successfully treated with imatinib therapy and hemihepatectomy.
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KEYWORD
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Gastrointestinal stromal tumors, Imatinib mesylate, Liver metastasis, Liver resection
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